{"id":239,"date":"2026-04-20T09:00:00","date_gmt":"2026-04-20T00:00:00","guid":{"rendered":"https:\/\/matsuhealth.com\/jp\/?p=239"},"modified":"2026-05-10T16:03:06","modified_gmt":"2026-05-10T07:03:06","slug":"fasting-nejm","status":"publish","type":"post","link":"https:\/\/matsuhealth.com\/jp\/fasting-nejm\/","title":{"rendered":"\u3010\u6700\u65b0\u7814\u7a76\u3067\u5224\u660e\ud83d\udd2c\u3011NEJM\u306a\u3069\u533b\u5b66\u8a8c\u304c\u8a3c\u660e\uff01\u65ad\u98df\u306e\u5065\u5eb7\u30e1\u30ea\u30c3\u30c8\u3092\u5fb9\u5e95\u89e3\u8aac"},"content":{"rendered":"<p>\u300c\u65ad\u98df\u3063\u3066\u3001\u672c\u5f53\u306b\u5065\u5eb7\u306b\u826f\u3044\u306e\uff1f\u79d1\u5b66\u7684\u306a\u6839\u62e0\u306f\u3042\u308b\u306e\uff1f\u300d<\/p>\n<p>\u305d\u3093\u306a\u7591\u554f\u3092\u6301\u3063\u3066\u3044\u308b\u65b9\u306f\u591a\u3044\u306e\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u304b\u3002<\/p>\n<p>\u5b9f\u306f\u3001\u65ad\u98df\uff08\u30a4\u30f3\u30bf\u30fc\u30df\u30c3\u30c6\u30f3\u30c8\u30d5\u30a1\u30b9\u30c6\u30a3\u30f3\u30b0\uff09\u306e\u52b9\u679c\u306f\u3001\u4e16\u754c\u3067\u6700\u3082\u6a29\u5a01\u3042\u308b\u533b\u5b66\u8a8c\u306e\u3072\u3068\u3064<span class=\"marker-thickYellow\"><strong>\u300c\u30cb\u30e5\u30fc\u30fb\u30a4\u30f3\u30b0\u30e9\u30f3\u30c9\u30fb\u30b8\u30e3\u30fc\u30ca\u30eb\u30fb\u30aa\u30d6\u30fb\u30e1\u30c7\u30a3\u30b7\u30f3\uff08NEJM\uff09\u300d<\/strong><\/span>\u3092\u306f\u3058\u3081\u3001\u591a\u304f\u306e\u4e00\u6d41\u7814\u7a76\u6a5f\u95a2\u306b\u3088\u3063\u3066\u79d1\u5b66\u7684\u306b\u8a3c\u660e\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u3053\u306e\u8a18\u4e8b\u3067\u306f\u3001\u6700\u65b0\u306e\u7814\u7a76\u30c7\u30fc\u30bf\u3092\u3082\u3068\u306b\u3001\u65ad\u98df\u304c\u3082\u305f\u3089\u3059\u5065\u5eb7\u30e1\u30ea\u30c3\u30c8\u3092\u308f\u304b\u308a\u3084\u3059\u304f\u89e3\u8aac\u3057\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n<div class=\"balloon\">\n<figure class=\"balloon__img balloon__img-left\">\n<div><\/div><figcaption class=\"balloon__name\">\u30de\u30c4<\/figcaption><\/figure>\n<div class=\"balloon__text balloon__text-right\">\u4e16\u754c\u30c8\u30c3\u30d7\u30af\u30e9\u30b9\u306e\u533b\u5b66\u8a8c\u304c\u65ad\u98df\u306e\u52b9\u679c\u3092\u8a8d\u3081\u3066\u3044\u308b\u3063\u3066\u3001\u77e5\u3063\u3066\u307e\u3057\u305f\u304b\uff1f\u50d5\u304c\u30d5\u30a1\u30b9\u30c6\u30a3\u30f3\u30b0\u3092\u59cb\u3081\u305f\u7406\u7531\u306e\u3072\u3068\u3064\u3082\u3001\u3053\u306e\u79d1\u5b66\u7684\u306a\u88cf\u4ed8\u3051\u304c\u3042\u3063\u305f\u304b\u3089\u306a\u3093\u3067\u3059\u3088\u306d\u3002<\/div>\n<\/div>\n<h2>\u4e16\u754c\u7684\u533b\u5b66\u8a8cNEJM\u304c\u65ad\u98df\u3092\u7279\u96c6\uff01\u305d\u306e\u7814\u7a76\u5185\u5bb9\u3068\u306f<\/h2>\n<p><figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/matsuhealth.com\/jp\/jp_wp\/wp-content\/themes\/the-thor\/img\/dummy.gif\" data-layzr=\"https:\/\/matsuhealth.com\/jp\/jp_wp\/wp-content\/uploads\/2026\/03\/fasting-nejm-jp-1.jpg\" alt=\"\u65ad\u98df\u306e\u6700\u65b0\u533b\u5b66\u7814\u7a76\" \/><figcaption style=\"font-size:8px;color:#999999;\">Photo by Tara Winstead \/ Pexels<\/figcaption><\/figure>\n<\/p>\n<h3>NEJM\u306e\u65ad\u98df\u7279\u96c6\u8ad6\u6587\u304c\u4e16\u754c\u306b\u4e0e\u3048\u305f\u885d\u6483<\/h3>\n<p>2019\u5e74\u3001NEJM\u306b\u63b2\u8f09\u3055\u308c\u305f\u30de\u30fc\u30af\u30fb\u30de\u30c3\u30c8\u30bd\u30f3\u535a\u58eb\uff08\u7c73\u56fd\u7acb\u8001\u5316\u7814\u7a76\u6240\uff09\u3089\u306b\u3088\u308b\u8ad6\u6587\u300c\u65ad\u98df\u306b\u3088\u308b\u4ee3\u8b1d\u30b9\u30a4\u30c3\u30c1\u30f3\u30b0\u3068\u5065\u5eb7\u3078\u306e\u5f71\u97ff\u300d\u306f\u3001\u533b\u7642\u30fb\u5065\u5eb7\u696d\u754c\u306b\u5927\u304d\u306a\u885d\u6483\u3092\u4e0e\u3048\u307e\u3057\u305f\u3002<\/p>\n<p>\u3053\u306e\u8ad6\u6587\u306f\u3001\u9593\u6b20\u7684\u65ad\u98df\u304c<span class=\"marker-thickYellow\"><strong>\u4f53\u91cd\u7ba1\u7406\u30fb\u8840\u7cd6\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u30fb\u8133\u6a5f\u80fd\u30fb\u6297\u708e\u75c7<\/strong><\/span>\u306a\u3069\u8907\u6570\u306e\u5065\u5eb7\u6307\u6a19\u3092\u6539\u5584\u3059\u308b\u3053\u3068\u3092\u3001\u5305\u62ec\u7684\u306a\u30ec\u30d3\u30e5\u30fc\u3068\u3057\u3066\u793a\u3057\u305f\u3082\u306e\u3067\u3059\u3002<\/p>\n<p>NEJM\u306f\u30ce\u30fc\u30d9\u30eb\u8cde\u53d7\u8cde\u8005\u3082\u591a\u6570\u8f29\u51fa\u3057\u3066\u304d\u305f\u4e16\u754c\u6700\u9ad8\u5cf0\u306e\u533b\u5b66\u8a8c\u306e\u3072\u3068\u3064\u3002\u305d\u3053\u306b\u65ad\u98df\u306e\u52b9\u679c\u304c\u63b2\u8f09\u3055\u308c\u305f\u3053\u3068\u306f\u3001\u65ad\u98df\u304c\u300c\u6c11\u9593\u7642\u6cd5\u300d\u3067\u306f\u306a\u304f\u300c\u79d1\u5b66\u7684\u306b\u88cf\u4ed8\u3051\u3089\u308c\u305f\u5065\u5eb7\u6cd5\u300d\u3067\u3042\u308b\u3053\u3068\u3092\u4e16\u754c\u306b\u793a\u3057\u305f\u51fa\u6765\u4e8b\u3067\u3057\u305f\u3002<\/p>\n<h3>\u65e5\u672c\u3067\u3082\u6ce8\u76ee\u304c\u96c6\u307e\u308b\u65ad\u98df\u7814\u7a76<\/h3>\n<p>\u65e5\u672c\u3067\u3082\u3001\u6771\u4eac\u5927\u5b66\u3084\u6176\u61c9\u7fa9\u587e\u5927\u5b66\u306a\u3069\u306e\u7814\u7a76\u6a5f\u95a2\u304c\u65ad\u98df\u3068\u5065\u5eb7\u306e\u95a2\u4fc2\u3092\u7814\u7a76\u3057\u3066\u304a\u308a\u3001\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\uff08\u7d30\u80de\u306e\u81ea\u98df\u4f5c\u7528\uff09\u306e\u767a\u898b\u3067\u30ce\u30fc\u30d9\u30eb\u533b\u5b66\u8cde\u3092\u53d7\u8cde\u3057\u305f\u5927\u9685\u826f\u5178\u6c0f\u306e\u7814\u7a76\u6210\u679c\u304c\u3001\u65ad\u98df\u3078\u306e\u79d1\u5b66\u7684\u95a2\u5fc3\u3092\u3055\u3089\u306b\u9ad8\u3081\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306f\u65ad\u98df\u4e2d\u306b\u6d3b\u6027\u5316\u3059\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u3067\u3001<span class=\"marker-thickYellow\"><strong>\u8001\u5316\u3057\u305f\u7d30\u80de\u306e\u30ea\u30b5\u30a4\u30af\u30eb\u3092\u4fc3\u3057\u3001\u75be\u60a3\u30ea\u30b9\u30af\u3092\u4e0b\u3052\u308b<\/strong><\/span>\u53ef\u80fd\u6027\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<div class=\"balloon\">\n<figure class=\"balloon__img balloon__img-left\">\n<div><\/div><figcaption class=\"balloon__name\">\u30de\u30c4<\/figcaption><\/figure>\n<div class=\"balloon__text balloon__text-right\">\u3053\u308c\u3060\u3051\u306e\u30e1\u30ea\u30c3\u30c8\u304c\u79d1\u5b66\u7684\u306b\u8a3c\u660e\u3055\u308c\u3066\u3044\u308b\u306a\u3089\u3001\u8a66\u3057\u3066\u307f\u306a\u3044\u624b\u306f\u306a\u3044\u3067\u3059\u3088\u306d\u3002\u50d5\u81ea\u8eab\u3001\u65ad\u98df\u3092\u59cb\u3081\u3066\u304b\u3089\u4f53\u91cd\u30fb\u8840\u7cd6\u30fb\u30e1\u30f3\u30bf\u30eb\u3059\u3079\u3066\u3067\u5b9f\u611f\u304c\u3042\u308a\u307e\u3057\u305f\u3002<\/div>\n<\/div>\n<h3>\u8457\u8005\u30de\u30c4\u306e\u4f53\u9a13\u8ac7<\/h3>\n<p>\u50d5\u304c\u30d5\u30a1\u30b9\u30c6\u30a3\u30f3\u30b0\u3092\u59cb\u3081\u305f\u306e\u306f\u3001\u3061\u3087\u3046\u3069NEJM\u306e\u8ad6\u6587\u304c\u8a71\u984c\u306b\u306a\u3063\u3066\u3044\u305f\u9803\u3067\u3057\u305f\u3002<\/p>\n<p>\u300c\u3053\u308c\u3060\u3051\u306e\u79d1\u5b66\u7684\u6839\u62e0\u304c\u3042\u308b\u306a\u3089\u3001\u8a66\u3057\u3066\u307f\u3088\u3046\u300d\u3068\u601d\u3063\u305f\u306e\u304c\u6700\u521d\u306e\u304d\u3063\u304b\u3051\u3067\u3059\u3002<\/p>\n<p>\u5b9f\u969b\u306b\u59cb\u3081\u3066\u307f\u308b\u3068\u3001\u8ad6\u6587\u306b\u66f8\u304b\u308c\u3066\u3044\u305f\u52b9\u679c\u3092\u81ea\u5206\u306e\u4f53\u3067\u30ea\u30a2\u30eb\u306b\u611f\u3058\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3057\u305f\u3002<\/p>\n<h2>\u7814\u7a76\u3067\u8a3c\u660e\u3055\u308c\u305f\u65ad\u98df\u306e5\u5927\u5065\u5eb7\u30e1\u30ea\u30c3\u30c8<\/h2>\n<p>NEJM\u3092\u542b\u3080\u8907\u6570\u306e\u7814\u7a76\u3067\u660e\u3089\u304b\u306b\u306a\u3063\u305f\u3001\u65ad\u98df\u306e\u4ee3\u8868\u7684\u306a\u5065\u5eb7\u30e1\u30ea\u30c3\u30c8\u30925\u3064\u3054\u7d39\u4ecb\u3057\u307e\u3059\u3002<\/p>\n<div class=\"ep-box bgc-VPturquoise\">\n<ul>\n<li><span class=\"marker-thickYellow\"><strong>\u2460 \u4f53\u91cd\u30fb\u4f53\u8102\u80aa\u306e\u6e1b\u5c11<\/strong><\/span>\uff1a\u65ad\u98df\u306b\u3088\u3063\u3066\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u304c\u6291\u3048\u3089\u308c\u3001\u4f53\u304c\u8102\u80aa\u3092\u30a8\u30cd\u30eb\u30ae\u30fc\u6e90\u3068\u3057\u3066\u4f7f\u3044\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002\u8907\u6570\u306eRCT\uff08\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\uff09\u3067\u4f53\u91cd\u30fb\u4f53\u8102\u80aa\u306e\u6709\u610f\u306a\u6e1b\u5c11\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059<\/li>\n<li><span class=\"marker-thickYellow\"><strong>\u2461 \u8840\u7cd6\u5024\u30fb\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u306e\u6539\u5584<\/strong><\/span>\uff1a2\u578b\u7cd6\u5c3f\u75c5\u30ea\u30b9\u30af\u306e\u4f4e\u6e1b\u306b\u95a2\u3059\u308b\u7814\u7a76\u304c\u591a\u6570\u3002\u7a7a\u8179\u6642\u8840\u7cd6\u3068HbA1c\u306e\u6539\u5584\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059<\/li>\n<li><span class=\"marker-thickYellow\"><strong>\u2462 \u8133\u6a5f\u80fd\u30fb\u8a8d\u77e5\u6a5f\u80fd\u306e\u5411\u4e0a<\/strong><\/span>\uff1aBDNF\uff08\u8133\u7531\u6765\u795e\u7d4c\u6804\u990a\u56e0\u5b50\uff09\u306e\u5897\u52a0\u306b\u3088\u308a\u3001\u5b66\u7fd2\u30fb\u8a18\u61b6\u30fb\u96c6\u4e2d\u529b\u304c\u5411\u4e0a\u3059\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059<\/li>\n<li><span class=\"marker-thickYellow\"><strong>\u2463 \u708e\u75c7\u30de\u30fc\u30ab\u30fc\u306e\u4f4e\u4e0b<\/strong><\/span>\uff1a\u6162\u6027\u708e\u75c7\u306f\u591a\u304f\u306e\u75be\u60a3\u306e\u6839\u672c\u539f\u56e0\u3002\u65ad\u98df\u306b\u3088\u3063\u3066CRP\u306a\u3069\u306e\u708e\u75c7\u30de\u30fc\u30ab\u30fc\u304c\u4f4e\u4e0b\u3059\u308b\u3053\u3068\u304c\u8907\u6570\u306e\u7814\u7a76\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059<\/li>\n<li><span class=\"marker-thickYellow\"><strong>\u2464 \u7d30\u80de\u306e\u82e5\u8fd4\u308a\uff08\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\uff09<\/strong><\/span>\uff1a\u65ad\u98df\u4e2d\u306b\u6d3b\u6027\u5316\u3059\u308b\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u304c\u3001\u8001\u5316\u7d30\u80de\u306e\u30ea\u30b5\u30a4\u30af\u30eb\u3092\u4fc3\u9032\u3057\u3001\u75be\u60a3\u4e88\u9632\u306b\u8ca2\u732e\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059<\/li>\n<\/ul>\n<\/div>\n<p>\u3053\u308c\u3089\u306e\u30e1\u30ea\u30c3\u30c8\u306f\u3059\u3079\u3066\u3001\u67fb\u8aad\u3092\u53d7\u3051\u305f\uff08\u5c02\u9580\u5bb6\u306b\u3088\u308b\u30c1\u30a7\u30c3\u30af\u6e08\u307f\u306e\uff09\u5b66\u8853\u8ad6\u6587\u306b\u3088\u3063\u3066\u652f\u6301\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u50d5\u81ea\u8eab\u3082\u65ad\u98df\u3092\u7d9a\u3051\u30663\u30f6\u6708\u3067\u4f53\u91cd\u304c15kg\u6e1b\u308a\u3001\u8840\u6db2\u691c\u67fb\u306e\u6570\u5024\u3082\u6539\u5584\u3057\u307e\u3057\u305f\u3002\u79d1\u5b66\u304c\u8a3c\u660e\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u81ea\u5206\u306e\u4f53\u3067\u3082\u5b9f\u611f\u3067\u304d\u305f\u306e\u306f\u3001\u672c\u5f53\u306b\u5927\u304d\u306a\u81ea\u4fe1\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n<h2>\u65ad\u98df\u304c\u52b9\u679c\u7684\u306a\u79d1\u5b66\u7684\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u89e3\u8aac<\/h2>\n<p><figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/matsuhealth.com\/jp\/jp_wp\/wp-content\/themes\/the-thor\/img\/dummy.gif\" data-layzr=\"https:\/\/matsuhealth.com\/jp\/jp_wp\/wp-content\/uploads\/2026\/03\/fasting-nejm-jp-2.jpg\" alt=\"\u65ad\u98df\u306e\u5065\u5eb7\u30e1\u30ea\u30c3\u30c8\u79d1\u5b66\u7684\u6839\u62e0\" \/><figcaption style=\"font-size:8px;color:#999999;\">Photo by www.kaboompics.com \/ Pexels<\/figcaption><\/figure>\n<\/p>\n<h3>\u300c\u4ee3\u8b1d\u30b9\u30a4\u30c3\u30c1\u30f3\u30b0\u300d\u304c\u9375\u3092\u63e1\u308b<\/h3>\n<p>\u65ad\u98df\u304c\u5065\u5eb7\u306b\u826f\u3044\u6700\u5927\u306e\u7406\u7531\u306f\u3001<span class=\"marker-thickPink\"><strong>\u300c\u4ee3\u8b1d\u30b9\u30a4\u30c3\u30c1\u30f3\u30b0\u300d<\/strong><\/span>\u3068\u547c\u3070\u308c\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u306b\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u901a\u5e38\u3001\u4f53\u306f\u30d6\u30c9\u30a6\u7cd6\uff08\u7cd6\u8cea\uff09\u3092\u30e1\u30a4\u30f3\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u6e90\u3068\u3057\u3066\u4f7f\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u65ad\u98df\u306b\u3088\u3063\u3066\u809d\u81d3\u306e\u30b0\u30ea\u30b3\u30fc\u30b2\u30f3\u304c\u67af\u6e07\u3059\u308b\u3068\u3001\u4f53\u306f\u8102\u80aa\u3092\u5206\u89e3\u3057\u3066\u30b1\u30c8\u30f3\u4f53\u3092\u4f5c\u308a\u51fa\u3057\u3001\u3053\u308c\u3092\u30a8\u30cd\u30eb\u30ae\u30fc\u3068\u3057\u3066\u4f7f\u3044\u59cb\u3081\u307e\u3059\u3002<\/p>\n<p>\u30b1\u30c8\u30f3\u4f53\u306f\u8133\u306b\u3068\u3063\u3066\u975e\u5e38\u306b\u52b9\u7387\u306e\u826f\u3044\u30a8\u30cd\u30eb\u30ae\u30fc\u6e90\u3067\u3001<span class=\"marker-thickYellow\"><strong>\u96c6\u4e2d\u529b\u30fb\u8a18\u61b6\u529b\u30fb\u7cbe\u795e\u5b89\u5b9a\u6027\u306e\u5411\u4e0a<\/strong><\/span>\u306b\u3064\u306a\u304c\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<h3>\u30a4\u30f3\u30b9\u30ea\u30f3\u30ec\u30d9\u30eb\u306e\u4f4e\u4e0b\u304c\u4f53\u3092\u5909\u3048\u308b<\/h3>\n<p>\u98df\u4e8b\u3092\u3057\u3066\u3044\u306a\u3044\u6642\u9593\u304c\u7d9a\u304f\u3068\u3001\u8840\u4e2d\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u6fc3\u5ea6\u304c\u5927\u304d\u304f\u4e0b\u304c\u308a\u307e\u3059\u3002<\/p>\n<p>\u30a4\u30f3\u30b9\u30ea\u30f3\u304c\u4f4e\u3044\u72b6\u614b\u3067\u306f\u3001\u8102\u80aa\u7d30\u80de\u304b\u3089\u8102\u80aa\u9178\u304c\u653e\u51fa\u3055\u308c\u3084\u3059\u304f\u306a\u308a\u3001\u8102\u80aa\u71c3\u713c\u304c\u9032\u307f\u307e\u3059\u3002\u307e\u305f\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u304c\u6539\u5584\u3055\u308c\u308b\u3053\u3068\u3067\u30012\u578b\u7cd6\u5c3f\u75c5\u306e\u4e88\u9632\u306b\u3082\u3064\u306a\u304c\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<h3>\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306b\u3088\u308b\u7d30\u80de\u306e\u81ea\u5df1\u4fee\u5fa9<\/h3>\n<p>\u65ad\u98df\u304c\u59cb\u307e\u3063\u3066\u7d0416\u6642\u9593\u304c\u7d4c\u904e\u3059\u308b\u3068\u3001\u7d30\u80de\u5185\u3067\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u304c\u6d3b\u6027\u5316\u3057\u307e\u3059\u3002<\/p>\n<p>\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u3068\u306f\u3001\u7d30\u80de\u304c\u53e4\u304f\u306a\u3063\u305f\u30bf\u30f3\u30d1\u30af\u8cea\u3084\u6a5f\u80fd\u4f4e\u4e0b\u3057\u305f\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3092\u5206\u89e3\u30fb\u518d\u5229\u7528\u3059\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u3067\u3059\u3002\u3053\u308c\u306b\u3088\u3063\u3066\u7d30\u80de\u304c\u82e5\u8fd4\u308a\u3001<span class=\"marker-thickYellow\"><strong>\u304c\u3093\u3084\u795e\u7d4c\u5909\u6027\u75be\u60a3\uff08\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u306a\u3069\uff09\u306e\u30ea\u30b9\u30af\u3092\u4e0b\u3052\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b<\/strong><\/span>\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u5b9f\u306f\u50d5\u3082\u3001\u65ad\u98df\u3092\u59cb\u3081\u3066\u304b\u3089\u306e\u307b\u3046\u304c\u98a8\u90aa\u3092\u3072\u304d\u306b\u304f\u304f\u306a\u3063\u305f\u3068\u611f\u3058\u3066\u3044\u307e\u3059\u3002\u4f53\u306e\u514d\u75ab\u6a5f\u80fd\u304c\u6574\u3063\u3066\u304d\u3066\u3044\u308b\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n<h2>\u3088\u304f\u3042\u308b\u8cea\u554f<\/h2>\n<h3>NEJM\u306b\u63b2\u8f09\u3055\u308c\u3066\u3044\u308b\u3068\u3044\u3046\u3053\u3068\u306f\u3001\u65ad\u98df\u306f\u533b\u5e2b\u3082\u63a8\u5968\u3057\u3066\u3044\u308b\u3068\u3044\u3046\u3053\u3068\uff1f<\/h3>\n<p>NEJM\u3078\u306e\u63b2\u8f09\u306f\u7814\u7a76\u7d50\u679c\u306e\u767a\u8868\u3067\u3042\u308a\u3001\u3059\u3079\u3066\u306e\u533b\u5e2b\u304c\u63a8\u5968\u3057\u3066\u3044\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u305f\u3060\u3057\u3001\u7279\u306b\u30e1\u30bf\u30dc\u30ea\u30c3\u30af\u30b7\u30f3\u30c9\u30ed\u30fc\u30e0\u30842\u578b\u7cd6\u5c3f\u75c5\u306e\u6539\u5584\u3092\u76ee\u6307\u3059\u6587\u8108\u3067\u306f\u3001\u9593\u6b20\u7684\u65ad\u98df\u3092\u63a8\u5968\u3059\u308b\u533b\u5e2b\u304c\u4e16\u754c\u7684\u306b\u5897\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u6301\u75c5\u304c\u3042\u308b\u65b9\u306f\u3001\u59cb\u3081\u308b\u524d\u306b\u304b\u304b\u308a\u3064\u3051\u533b\u306b\u76f8\u8ac7\u3059\u308b\u3053\u3068\u3092\u304a\u3059\u3059\u3081\u3057\u307e\u3059\u3002<\/p>\n<h3>\u65ad\u98df\u306e\u7814\u7a76\u306f\u3069\u306e\u304f\u3089\u3044\u4fe1\u983c\u3067\u304d\u308b\uff1f<\/h3>\n<p>\u65ad\u98df\u7814\u7a76\u306e\u591a\u304f\u306fRCT\uff08\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\uff09\u3084\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\uff08\u8907\u6570\u7814\u7a76\u306e\u7d71\u5408\u89e3\u6790\uff09\u306a\u3069\u3001\u4fe1\u983c\u6027\u306e\u9ad8\u3044\u624b\u6cd5\u3067\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u305f\u3060\u3057\u7814\u7a76\u671f\u9593\u304c\u77ed\u3044\u3082\u306e\u3084\u88ab\u9a13\u8005\u6570\u304c\u5c11\u306a\u3044\u3082\u306e\u3082\u3042\u308a\u3001\u9577\u671f\u7684\u306a\u52b9\u679c\u306b\u3064\u3044\u3066\u306f\u5f15\u304d\u7d9a\u304d\u7814\u7a76\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<h3>\u65ad\u98df\u306f\u3069\u306e\u304f\u3089\u3044\u306e\u671f\u9593\u3067\u52b9\u679c\u304c\u51fa\u59cb\u3081\u308b\uff1f<\/h3>\n<p>\u591a\u304f\u306e\u7814\u7a76\u3067\u306f\u30012\u301c4\u9031\u9593\u306e\u65ad\u98df\u3067\u4f53\u91cd\u30fb\u8840\u7cd6\u30fb\u708e\u75c7\u30de\u30fc\u30ab\u30fc\u306b\u5909\u5316\u304c\u73fe\u308c\u59cb\u3081\u307e\u3059\u3002\u4f53\u611f\u30ec\u30d9\u30eb\u3067\u306f\u30011\u9031\u9593\u307b\u3069\u3067\u300c\u982d\u304c\u30b9\u30c3\u30ad\u30ea\u3057\u305f\u300d\u300c\u7a7a\u8179\u611f\u304c\u843d\u3061\u7740\u3044\u3066\u304d\u305f\u300d\u3068\u611f\u3058\u308b\u65b9\u304c\u591a\u3044\u3088\u3046\u3067\u3059\u3002<\/p>\n<h3>16\u6642\u9593\u65ad\u98df\u4ee5\u5916\u306e\u65b9\u6cd5\uff085:2\u30c0\u30a4\u30a8\u30c3\u30c8\u306a\u3069\uff09\u3082\u52b9\u679c\u306f\u540c\u3058\uff1f<\/h3>\n<p>\u7814\u7a76\u3067\u306f16:8\u65ad\u98df\uff081\u65e516\u6642\u9593\u65ad\u98df\uff09\u3060\u3051\u3067\u306a\u304f\u3001\u90312\u65e5\u306e\u30ab\u30ed\u30ea\u30fc\u5236\u9650\uff085:2\u30c0\u30a4\u30a8\u30c3\u30c8\uff09\u306a\u3069\u3082\u540c\u69d8\u306e\u52b9\u679c\u3092\u793a\u3059\u3082\u306e\u304c\u3042\u308a\u307e\u3059\u3002\u81ea\u5206\u306e\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u306b\u5408\u3063\u305f\u65b9\u6cd5\u3092\u9078\u3076\u3053\u3068\u304c\u3001\u9577\u7d9a\u304d\u306e\u79d8\u8a23\u3067\u3059\u3002<\/p>\n<h2>\u79d1\u5b66\u304c\u8a3c\u660e\u3057\u305f\u65ad\u98df\u3067\u3001\u5065\u5eb7\u306a\u4f53\u3068\u8133\u3092\u4eca\u65e5\u304b\u3089\u624b\u306b\u5165\u308c\u3088\u3046<\/h2>\n<p><figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/matsuhealth.com\/jp\/jp_wp\/wp-content\/themes\/the-thor\/img\/dummy.gif\" data-layzr=\"https:\/\/matsuhealth.com\/jp\/jp_wp\/wp-content\/uploads\/2026\/03\/fasting-nejm-jp-3.jpg\" alt=\"\u5065\u5eb7\u7684\u306a\u4f53\u3068\u8133\" \/><figcaption style=\"font-size:8px;color:#999999;\">Photo by Anna Shvets \/ Pexels<\/figcaption><\/figure>\n<\/p>\n<p>NEJM\u3092\u306f\u3058\u3081\u3068\u3059\u308b\u4e16\u754c\u30c8\u30c3\u30d7\u306e\u533b\u5b66\u8a8c\u304c\u8a3c\u660e\u3057\u305f\u65ad\u98df\u306e\u5065\u5eb7\u30e1\u30ea\u30c3\u30c8\u3002\u5358\u306a\u308b\u6d41\u884c\u30c0\u30a4\u30a8\u30c3\u30c8\u3067\u306f\u306a\u304f\u3001\u79d1\u5b66\u7684\u306b\u88cf\u4ed8\u3051\u3089\u308c\u305f\u5065\u5eb7\u7fd2\u6163\u3067\u3059\u3002<\/p>\n<p>\u4ee3\u8b1d\u30b9\u30a4\u30c3\u30c1\u30f3\u30b0\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u306e\u6539\u5584\u3001\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306e\u6d3b\u6027\u5316\u2014\u2014\u3053\u308c\u3089\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u304c\u7d44\u307f\u5408\u308f\u3055\u308b\u3053\u3068\u3067\u3001\u4f53\u91cd\u30fb\u8840\u7cd6\u30fb\u8133\u6a5f\u80fd\u30fb\u7d30\u80de\u306e\u82e5\u8fd4\u308a\u306a\u3069\u3001\u591a\u9762\u7684\u306a\u5065\u5eb7\u6539\u5584\u3092\u3082\u305f\u3089\u3057\u307e\u3059\u3002<\/p>\n<p>\u96e3\u3057\u304f\u8003\u3048\u306a\u304f\u3066\u5927\u4e08\u592b\u3067\u3059\u3002\u307e\u305a\u306f\u300c\u5915\u98df\u304b\u3089\u7fcc\u65e5\u306e\u663c\u98df\u307e\u3067\u98df\u3079\u306a\u3044\u300d\u3068\u3044\u304616\u6642\u9593\u65ad\u98df\u304b\u3089\u59cb\u3081\u308b\u3060\u3051\u3067\u3001\u3053\u308c\u3089\u306e\u52b9\u679c\u3092\u4f53\u611f\u3057\u59cb\u3081\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n<div class=\"balloon\">\n<figure class=\"balloon__img balloon__img-left\">\n<div><\/div><figcaption class=\"balloon__name\">\u30de\u30c4<\/figcaption><\/figure>\n<div class=\"balloon__text balloon__text-right\">\u79d1\u5b66\u7684\u306a\u8a3c\u62e0\u304c\u3053\u3053\u307e\u3067\u305d\u308d\u3063\u3066\u3044\u308b\u5065\u5eb7\u6cd5\u306f\u306a\u304b\u306a\u304b\u3042\u308a\u307e\u305b\u3093\u3002\u307e\u305a16\u6642\u9593\u65ad\u98df\u304b\u3089\u59cb\u3081\u3066\u307f\u3066\u304f\u3060\u3055\u3044\u3002\u304d\u3063\u3068\u5909\u5316\u3092\u5b9f\u611f\u3067\u304d\u308b\u306f\u305a\u3067\u3059\u3002<\/div>\n<\/div>\n<div class=\"ep-box bgc-VPturquoise\">\n<p>\u25bc\u3042\u308f\u305b\u3066\u8aad\u307f\u305f\u3044<\/p>\n<ul>\n<li><a href=\"https:\/\/matsuhealth.com\/jp\/if-fasting\/\">\u30a4\u30f3\u30bf\u30fc\u30df\u30c3\u30c6\u30f3\u30c8\u30d5\u30a1\u30b9\u30c6\u30a3\u30f3\u30b0\uff08IF\uff09\u5b8c\u5168\u30ac\u30a4\u30c9<\/a><\/li>\n<li><a href=\"https:\/\/matsuhealth.com\/jp\/brain-fasting\/\">\u65ad\u98df\u3067\u8133\u304c\u5143\u6c17\u306b\u306a\u308b\u4ed5\u7d44\u307f<\/a><\/li>\n<li><a href=\"https:\/\/matsuhealth.com\/jp\/alzheimer-diet\/\">\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u4e88\u9632\u306e\u98df\u751f\u6d3b<\/a><\/li>\n<li><a href=\"https:\/\/matsuhealth.com\/jp\/fasting-science\/\">16\u6642\u9593\u65ad\u98df\u3067\u8840\u5727\u30fb\u8840\u7cd6\u5024\u6539\u5584\uff01\u79d1\u5b66\u7684\u30c7\u30fc\u30bf\u3067\u89e3\u8aac<\/a><\/li>\n<\/ul>\n<\/div>\n<p>\u25bc\u3053\u306e\u8a18\u4e8b\u306f\u4ee5\u4e0b\u306e\u52d5\u753b\u3067\u3082\u89e3\u8aac\u304c\u898b\u308c\u307e\u3059<\/p>\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube\">\n<div class=\"wp-block-embed__wrapper\"><iframe width=\"560\" height=\"315\" src=\"https:\/\/www.youtube.com\/embed\/D3BQeWJy1us\" title=\"YouTube video player\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; 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allowfullscreen><\/iframe><\/div>\n<\/figure>\n","protected":false},"excerpt":{"rendered":"<p>NEJM\u306a\u3069\u4e16\u754c\u30c8\u30c3\u30d7\u306e\u533b\u5b66\u8a8c\u304c\u8a3c\u660e\u3057\u305f\u65ad\u98df\u306e\u5065\u5eb7\u30e1\u30ea\u30c3\u30c8\u3092\u89e3\u8aac\u3002\u4ee3\u8b1d\u30b9\u30a4\u30c3\u30c1\u30f3\u30b0\u30fb\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u30fbBDNF\u5897\u52a0\u306a\u3069\u3001\u79d1\u5b66\u7684\u6839\u62e0\u306e\u3042\u308b\u65ad\u98df\u52b9\u679c\u3092\u5fb9\u5e95\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n","protected":false},"author":1,"featured_media":238,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[15,48,11,5,49],"class_list":["post-239","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-data","tag-15","tag-nejm","tag-11","tag-5","tag-49"],"_links":{"self":[{"href":"https:\/\/matsuhealth.com\/jp\/wp-json\/wp\/v2\/posts\/239","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/matsuhealth.com\/jp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/matsuhealth.com\/jp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/matsuhealth.com\/jp\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/matsuhealth.com\/jp\/wp-json\/wp\/v2\/comments?post=239"}],"version-history":[{"count":2,"href":"https:\/\/matsuhealth.com\/jp\/wp-json\/wp\/v2\/posts\/239\/revisions"}],"predecessor-version":[{"id":714,"href":"https:\/\/matsuhealth.com\/jp\/wp-json\/wp\/v2\/posts\/239\/revisions\/714"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/matsuhealth.com\/jp\/wp-json\/wp\/v2\/media\/238"}],"wp:attachment":[{"href":"https:\/\/matsuhealth.com\/jp\/wp-json\/wp\/v2\/media?parent=239"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/matsuhealth.com\/jp\/wp-json\/wp\/v2\/categories?post=239"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/matsuhealth.com\/jp\/wp-json\/wp\/v2\/tags?post=239"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}